‘Men In Pink’ raise raise money for Breast Cancer Alliance
‘Men In Pink’ raise raise money for Breast Cancer Alliance
The Breast Cancer Alliance, a Greenwich-based charitable organization, held its first annual Pink Party at The Loading Dock in Stamford on June 16. It was an evening of drinks, dinner and dancing to help raise awareness of and funding for the Breast Cancer Alliance (BCA) in their mission to find a cure. Kicking off the evening First Selectman Peter Tesei read a proclamation declaring June 16 Men …
Read more on Greenwich Post
Susan G. Komen for the Cure Advocacy Alliance
Story of how one breast cancer survivor fell through the cracks of the system and how we helped them.
Terramed Alliance News Moderate Alcohol Consumption Increases Risk of Cancer in Women
Terramed Alliance News Moderate Alcohol Consumption Increases Risk of Cancer in Women
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Home Page > Health > Terramed Alliance News Moderate Alcohol Consumption Increases Risk of Cancer in Women
Terramed Alliance News Moderate Alcohol Consumption Increases Risk of Cancer in Women
Posted: Nov 01, 2009 |Comments: 0
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The best “treatment” for cancer is to prevent it from occurring. Research is ongoing to evaluate environmental and lifestyle factors that may be associated with an increased incidence of cancer. Identifying such risk factors may allow individuals to modify lifestyle choices in order to reduce their risk of developing cancer.
The Million Women Study in the United Kingdom involved over 1.3 million middle-aged women who responded to a questionnaire regarding sociodemographic and personal information, including alcohol consumption. These women were followed for several years in an effort to determine how reproductive and lifestyle factors affect women’s health.
The current study used the data from just over 1.2 million of the women in the Million Women Study, excluding some women based on pre-existing cancers or because pertinent information was excluded on the questionnaire. About one-quarter of the cohort reported drinking no alcohol. Of the remaining women who reported consuming alcohol, 98% consumed fewer than 21 drinks per week, with the average being one drink per day. (Fewer than three drinks per day is considered low to moderate alcohol consumption.)
The women were followed for an average of 7.2 years, during which 68,775 invasive cancers occurred. Increased alcohol consumption was associated with increased risks of some cancers. With each additional drink consumed per day, the risk of breast cancer increased by 11%, oral cavity/pharynx cancer by 29%, esophageal cancer by 22%, larynx cancer by 44%, liver cancer by 24%, and total cancer by 6%.
The researchers concluded that low to moderate alcohol consumption increases the risk of certain cancers. Journal of the National Cancer Institute. 2009
Terramed Alliance is a non-profit charity organization dedicated to research, education and advocacy of breast cancer. One of the vision of Terramed Alliance is to provide this community and Internet users with a charity based research and education entity. Advocacy of breast cancer through education is vital to the reduction of this disease. For any requests and enquiries, please contact at us: cancer@terramedalliance.us www.terramedalliance.us
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Terramed Alliance is a non-profit charity organization dedicated to research, education and advocacy of breast cancer. One of the vision of Terramed Alliance is to provide this community and Internet users with a charity based research and education entity. Advocacy of breast cancer through education is vital to the reduction of this disease. For any requests and enquiries, please contact at us: cancer@terramedalliance.us www.terramedalliance.us
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Categories: Breast Cancer Risks Tags: Alcohol, Alliance, cancer, Consumption, Increases, moderate, News, Risk, Terramed, women
Alliance HealthCare Services Reaffirms 2010 Guidance and Announces Full Year 2011 Financial Guidance; Announces …
Alliance HealthCare Services Reaffirms 2010 Guidance and Announces Full Year 2011 Financial Guidance; Announces …
NEWPORT BEACH, Calif.–(BUSINESS WIRE)–Alliance HealthCare Services, Inc. (NYSE:AIQ) (the “Company” or “Alliance”), a leading national provider of outpatient diagnostic imaging and radiation therapy services, reaffirmed full year 2010 guidance and announced financial guidance for full year 2011. Full Year 2010 Guidance The Company reaffirms its full year 2010 revenue and Adjusted EBITDA …
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Categories: Breast Cancer Risks Tags: 2010, 2011, Alliance, Announces, financial, full, guidance, Healthcare, Reaffirms, Services, year
Health: Terra med Alliance News FDA Approved Leukemia Drugs Shows Promise In Ovarian Cancer Cells
Terra med Alliance News: The drug Sprycel, approved for use by the U.S. Food and Drug Administration in patients with chronic myeloid leukemia, significantly inhibited the growth and invasiveness of ovarian cancer cells and also promoted their death, a study by researchers with UCLA’s Jonsson Comprehensive Cancer Center found.
Terra med Alliance News: The drug, when paired with a chemotherapy regimen, was even more effective in fighting ovarian cancer in cell lines in which signaling of the Src family kinases, associated with the deadly disease, is activated.
The study appears in the Nov. 10, 2009 edition of the British Medical Journal.
Ovarian cancer, which will strike 21,600 women this year and kill 15,500, causes more deaths than any other cancer of the female reproductive system. Few effective therapies for ovarian cancer exist, so it would be advantageous for patients if a new drug could be found that fights the cancer, said Gottfried Konecny, an assistant professor of hematology/oncology, a Jonsson Cancer Center researcher and first author of the study.
“I think Sprycel could be a potential additional drug for treating patients with Src dependent ovarian cancer,” Konecny said. “It is important to remember that this work is only on cancer cell lines, but it is significant enough that it should be used to justify clinical trials to confirm that women with this type of ovarian cancer could benefit.”
Recent gene expression studies have shown that about one-third of women have ovarian cancers with activated Src pathways, so the drug could potentially help 7,000 ovarian cancer patients every year.
In this study, the UCLA team tested the drug against 34 ovarian cancer cell lines and they conducted genetic analysis on all cell lines. Through these analyses, the researchers were able to identify genes that predict response to Sprycel. If the work is confirmed in human studies, it may be possible to test patients for Src activation and select those who would respond prior to treatment, personalizing their care.
“We were able to identify markers in the pre-clinical setting that would allow us to predict response to Sprycel,” Konecny said. “These may help us in future clinical trials in selecting patients for studies of the drug.”
Sprycel is what is known as a “dirty” kinase inhibitor, meaning it inhibits more than one pathway. Konecny said it also inhibits the focal adhesion kinase and ephrin receptor, also associated with ovarian cancer.
The next step, Konecny said, would be to test the drug on women with ovarian cancer in a clinical trial. The tissue of responders would then be analyzed to determine if the Src and other pathways were activated. If that is confirmed, it would further prove that Sprycel could be used to fight ovarian cancer. In studies, women would be screened before entering a trial and only those with Src dependent cancers could be enrolled to provide further evidence, Konecny said, much like the studies of the molecularly targeted breast cancer drug Herceptin enrolled only women who had HER-2 positive disease.
“Herceptin is different because we knew in advance that the only worked in women with HER-2 amplification,” he said. “In this case, we don’t clearly know that yet. The data reassure us that the drug works where the targets are over-expressed but we need more testing to confirm this.”
The tests combining the drug with chemotherapy are significant because chemotherapy currently is the first line treatment for ovarian cancer patients following surgery. Because Sprycel proved to have a synergistic effect when combined with chemotherapy — both made the other work better — it may be possible to add the targeted therapy as a first line treatment if its efficacy is confirmed in future studies, adding a new tool to an oncologist’s arsenal. Adapted from materials provided by University of California – Los Angeles, via EurekAlert!, a service of AAAS.
Terra med Alliance is a non-profit organization in the battle against leukemia helps children living with cancer and their families. Our goal is to make sure children battling cancer know they are not alone. For more information please visit www.terramedalliance.org. Email at contact@terramedalliance.org