FDA issues Complete Response letter for Avodart sNDA for reduction of prostate cancer risk
FDA issues Complete Response letter for Avodart sNDA for reduction of prostate cancer risk
GlaxoSmithKline (GSK) today announced that the Company has received a Complete Response letter from the U.S. Food and Drug Administration (FDA) for the supplemental New Drug Application (sNDA) for Avodart® (dutasteride) for reducing the risk of prostate cancer in men at increased risk for the disease, defined as those who have had a prior negative biopsy due to clinical concern and have an …
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Categories: Breast Cancer Treatment Tags: Avodart, cancer, Complete, Issues, Letter, prostate, reduction, Response, Risk, sNDA
Generic Breast Cancer Medications ? Planning Treatment and Risk Reduction
If you or a loved has been diagnosed with breast cancer you know it can be a very confusing moment; after the initial shock a treatment must be chosen. In the advances to find a cure for breast cancer a wide range of treatment options are offered and among them is drug therapy. Women and their physicians opt for drug therapy as it is effective in treating cancer cells that have spread and is non-invasive. Picking your treatment therapy will take a lot of careful thought as it will not be the same for every woman. A plan must be chosen depending on your unique situation as cancer medications are not cheap. No matter which treatment method is chosen oral cancer prescription drugs are always part of the combination.
Once your doctor prescribed the right combination of treatments you have to understand your prescription. I will discuss 3 different drugs that are widely prescribed to treat breast cancer and prevent recurrence. The first drug is:
Tamoxifen aka Nolvadex is a drug categorized as antineoplastics; it works by blocking the effects of estrogen in the body which is required for cancer cells to grow. This medication is known to be an anti-estrogen medication. The chemical drug Tamoxifen was discovered by Astra Zeneca and is among the first breast cancer medications to be created. There is no patent over Nolvadex anymore therefore you can buy generic Tamoxifen.
Anastrozole aka Arimidex is also a drug known as an antineoplastic but unlike Tamoxifen it activates an enzyme know at aromatase. Anastrozole is a non-steroidal aromatase inhibitor which cuts off the supply of estrogen that cancer cells need to grow and survive. Anastrozole was also created by Astra Zeneca and is sold under the brand Arimidex. The patent over Arimidex expires in 2010 in the US but generic Arimidex is available in Canadian pharmacies as Anastrozole.
Letrozole aka Femara is also a non-steroidal aromatase inhibitor that works but this medication is used after surgery has been performed. Unlike Tamoxifen and Anastrozole, this medication is used to treat advanced breast cancer in postmenopausal women. Also Femara reduces the risk of breast cancer recurrence in women who have been treated for early-stage breast cancer with Tamoxifen for 5 years. Generic Femara is available in Online Canadian Pharmacies but not in US pharmacies.
The cost of treating breast cancer in the US is enormous; for example, the retail price of Femara is approximately $1,015 monthly. For that reason many women are researching cheaper alternatives for filling their prescriptions. Luckily generic cancer medications from Canada are available. If you do your research thoroughly you can find a fully licensed Canadian Online Pharmacy to fill your prescription safely and affordably.
Categories: Breast Cancer Risks Tags: breast, cancer, Generic, Medications, planning, reduction, Risk, Treatment
Male Breast Reduction
Male Breast Reduction
A popular cosmetic surgery for men may also be a surprising one-male breast reduction. This procedure is typically performed to treat a condition known as gynecomastia (enlarged breast tissue in men) or breasts enlarged as a result of fatty deposits from obesity. Gynecomastia can affect men of any age. According to a report published by The Mayo Clinic, it occurs as a result of a hormonal …
Read more on Medical News Today
Categories: Breast Cancer Information Tags: breast, Male, reduction
FDA Grants Priority Review Designation to Denosumab Biologics License Application for the Reduction of Skeletal …
FDA Grants Priority Review Designation to Denosumab Biologics License Application for the Reduction of Skeletal …
Amgen today announced that the U.S. Food and Drug Administration has granted priority review designation to denosumab, a subcutaneous RANK Ligand inhibitor, for the treatment of bone metastases to reduce skeletal related events in patients with cancer.
Read more on PR Newswire via Yahoo! Finance
Categories: Breast Cancer Risks Tags: application, Biologics, Denosumab, Designation, Grants, License, priority, reduction, Review, Skeletal
Male Breast Reduction: Lowering Confidence Two at a Time
Beach season is upon us, which can only mean one thing for men suffering with gynecomastia- swimming with your shirt on. Gynecomastia, more commonly referred to as â??man-boobsâ?, is not uncommon, as it is estimated to affect somewhere between 40%-60% of the male population. So take a second gents, lift up your shirts and have a long, hard look. If you see something sagging, male breast reduction could be for you!
What is it?
But what exactly does gynecomastia correction surgery entail? First and foremost, it is wise to get a mammogram or breast x-ray prior to surgery, which can rule out any serious, albeit unlikely, causes of gynecomastia such as breast cancer or tumors. Generally, male breast enlargement is due to either excess glandular tissue in the chest or excess fatty tissue in the chest.
In cases where glandular tissue is the primary cause, a small incision will be made around the edge of the areola or somewhere under the arm. From there, the surgeon will extract not only unnecessary tissue, but also excess fat and skin from around the nipple, as well as the bottom and sides of the breast in question. In cases where fatty tissue is the culprit, liposuction may be the only procedure needed. In which case, a small incision is made around the areola or somewhere in the armpit so that a cannula (a tube that drains fluids) can be inserted to suck out the fat.
Who needs it?
If you are feeling self-conscious about your gynecomastia, which in Greek roughly translates to the not-so-subtle â??woman- like breastsâ?, then maybe male breast reduction will work for you. However, if you are feeling self-conscious because you are a 13-year old boy going through puberty, the best idea is to wait it out. Though gynecomastia is common during puberty, it is generally a passing phase that will correct itself over the course of a few months. So hang in there young men, donâ??t let those Greek jerks get you down by comparing you to women.
Gynecomastia can stem from several different factors, the most obvious being obesity. However, other causes include genetic disorders, side effects from medication, chronic liver disease, aging, and steroid use. Drugs or medication that enhance estrogen or inhibit testosterone synthesis are generally the ones that produce gynecomastia, although drugs as common as alcohol, marijuana, and valium may also contribute to your â??woman- like breastsâ? physique.
The best candidates should be healthy, emotionally stable men of any age. It is ideal that the patient has firm, elastic skin so that it will reshape to the bodyâ??s new form. In some cases, surgery may be unnecessary, especially if your condition of gynecomastia is due to lifestyle preferences. If you are obese, for example, simple exercise and weight loss will minimize body fat, which may in turn decrease fatty tissue within the chest. Likewise, if you drink alcohol in excessive amounts or smoke a lot of marijuana (weâ??re talking High Times subscriber level) it may be best to cease consumption for several weeks to see if any reversal signs of gynecomastia occur.
Benefits
There is a significant difference in before-and-after pictures (check it out online if youâ??re into that sort of thing). Not only is the surgery permanent, but it is fairly simple and in the most common cases, involves only one incision that is generally well-disguised either on the edge of the areola or under the arm.
However, the biggest benefit is the boost in confidence, seeing as how a lack of confidence is the primary reason why most men get breast reduction surgery in the first place. Get ready to seek out friends who throw lots of pool parties.
Risks?
If you are being treated by a qualified plastic surgeon (i.e. not some guy you met behind Safeway) then complications should be rare or minor at best. However, surgery of any kind can be risky. Possible risks include infection, skin injury, excessive bleeding, adverse reaction to anesthesia and excessive fluid loss or accumulation. Noticeable scars are possible (especially when major breast reductions are involved) as well as permanent pigment changes around the breast and slightly asymmetric nipples. Temporary effects may include a numbness of the breast or loss of sensation, which could potentially last up to a year.
If youâ??re afraid of taking your shirt off this beach season, you may want to consider male breast reduction. Unless the beach in question is Coney Island, in which case, who cares if you have man-boobs? Have a Coney Dog and relax.
The information in the article is not intended to substitute for the medical expertise and advice of your health care provider. We encourage you to discuss any decisions about treatment or care with an appropriate health care provider.
Categories: Breast Cancer Questions & Answers Tags: breast, Confidence, Lowering, Male, reduction, Time
Breast Reduction Surgery India- Affordable Cost Breast Reduction India
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Breast Reduction Surgery India
Breast Reduction Surgery
Many women with very large breasts suffer physical discomfort, bad posture and embarrassment. More and more women are now opting for breast reduction surgery.
Having very large breasts can cause back and breast pain as well as low self-esteem. You may be very self-conscious and resort to wearing loose clothing to conceal your shape. Breast reduction surgery can help restore proportion to your body, help you carry out those activities that you couldnâ??t before and regain any lost self-confidence…
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The Breast Reduction Procedure
The breast reduction operation involves the removal of fat and excess skin to create a great new size and shape. The cosmetic surgeon will reposition your nipple and areola to give the breast a natural appearance…
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Who is best for Breast Reduction ?
Breast Reduction can improve your appearance and your self-confidence. Before you decide to have surgery, think carefully about your expectations, and feel free to discuss them thoroughly during your consultation.
The best candidates for Breast Reduction are women with breasts that are too large in proportion to their body frame, women with pendulous breasts with nipples that point downward, woman with a large size difference between breasts, women with back, neck or shoulder pain caused by breast weight, women who suffer skin irritation beneath the breasts, women who must restrict their physical activity or the way they dress due to the size and weight of their breasts or women with self-consciousness about the largeness of their breasts…
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Who Should Not Have Breast Reduction Surgery ?
Breast reduction surgery is not recommended for women with : -
Breast cancer Uncontrolled diabetes Cellulitis (infection of the soft tissue of the breast) Hardened breast skin Dry or broken breast skin Surgery…
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Recovery
It may take 6 months to a year for breasts to settle into their new shape, but swelling and bruising will disappear in the first few weeks. May ache for a couple of weeks. Should avoid lifting or pushing anything heavy for 3 to 4 weeks. Back to work (if not too strenuous) and social activities: about 2 weeks….
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Please log on to : www.indiahospitaltour.com
Send your query : Get a Quote
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We Care Core Values
We have a very simple business model that keeps you as the centre.
Having the industryâ??s most elaborate and exclusive Patient Care and Clinical Coordination teams stationed at each partner hospital, we provide you the smoothest and seamless care ever imagined. With a ratio of one Patient Care Manager to five patients our patient care standards are unmatched across the sub continent.
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Categories: Breast Cancer Recovery Tags: affordable, breast, cost, India, reduction, surgery
Breast Reduction Surgery in Abroad at Affordable Cost-Breast Reduction
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Breast Reduction Surgery Abroad
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Breast Reduction Surgery
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Many women with very large breasts suffer physical discomfort, bad posture and embarrassment. More and more women are now opting for breast reduction surgery.
Having very large breasts can cause back and breast pain as well as low self-esteem. You may be very self-conscious and resort to wearing loose clothing to conceal your shape. Breast reduction surgery can help restore proportion to your body, help you carry out those activities that you couldnâ??t before and regain any lost self-confidence…
Â
The Breast Reduction Procedure
The breast reduction operation involves the removal of fat and excess skin to create a great new size and shape. The cosmetic surgeon will reposition your nipple and areola to give the breast a natural appearance…
Â
Who is best for Breast Reduction ?
Breast Reduction can improve your appearance and your self-confidence. Before you decide to have surgery, think carefully about your expectations, and feel free to discuss them thoroughly during your consultation.
The best candidates for Breast Reduction are women with breasts that are too large in proportion to their body frame, women with pendulous breasts with nipples that point downward, woman with a large size difference between breasts, women with back, neck or shoulder pain caused by breast weight, women who suffer skin irritation beneath the breasts, women who must restrict their physical activity or the way they dress due to the size and weight of their breasts or women with self-consciousness about the largeness of their breasts…
Â
Who Should Not Have Breast Reduction Surgery ?
Breast reduction surgery is not recommended for women with : -
Breast cancer Uncontrolled diabetes Cellulitis (infection of the soft tissue of the breast) Hardened breast skin Dry or broken breast skin Surgery…
Â
Recovery
It may take 6 months to a year for breasts to settle into their new shape, but swelling and bruising will disappear in the first few weeks. May ache for a couple of weeks. Should avoid lifting or pushing anything heavy for 3 to 4 weeks. Back to work (if not too strenuous) and social activities: about 2 weeks….
Â
Please log on to : www.indiahospitaltour.com
Send your query : Get a Quote
Â
We Care Core Values
We have a very simple business model that keeps you as the centre.
Having the industryâ??s most elaborate and exclusive Patient Care and Clinical Coordination teams stationed at each partner hospital, we provide you the smoothest and seamless care ever imagined. With a ratio of one Patient Care Manager to five patients our patient care standards are unmatched across the sub continent.
Â
Categories: Breast Cancer Recovery Tags: abroad, affordable, breast, CostBreast, reduction, surgery
Breast Reduction
For many women, having large breasts is a curse rather than a blessing. Naturally large breasts have a tendency to sag and can be extremely uncomfortable both physically and psychologically. If you have breasts that give you back pain, cause irritation around your bra straps, give you skin rashes, or make you feel uncomfortable in social situations then a breast reduction operation may be the answer to solving your problems.
Benefits to Breast Reduction
• Less weight in front, making chronic back and neck pain go away
• New breasts support themselves better, making your bra have to do less work
• Reduced breasts are often given whatever shape and size the patient wants for a more pleasing overall figure
• Increased overall comfort and confidence for the patient
• Improved posture
• Lower risk of breast cancer
• Promotes a more active lifestyle
• More clothing options
Potential Risk of Breast Reduction
• Loss of feeling around the nipples
• Delayed healing
• Scars
• Inability to breast feed
• Infection
Despite the potential risks to a breast reduction operation, the vast majority of women who receive breast reduction surgery are extremely pleased with the results and show a marked improvement across the board on psychological testing that measures confidence and quality of life.
Recovery
A breast reduction surgery is performed in the hospital and, depending on the surgeon and your ability to heal, recovery time will vary. For the first two weeks after a breast reduction you can expect to have bruising and have to wear a surgical bra to ensure that there is a minimum of motion in that area.
In the first few weeks after a breast reduction you are advised to avoid any heavy lifting or otherwise strenuous activity. It is also recommended that any contact with the breasts be very gentle for at least four to six weeks after surgery. Because the tissue being removed from the breasts is so sensitive, it can take six months to a year for the patient to see the final results from their operation.
Categories: Breast Cancer Recovery Tags: breast, reduction
Male Breast Reduction Surgery – Gynecomastia
Gynecomastia is a medical term that comes from the Greek words for “women-like breasts.” Though this oddly named condition is rarely talked about, it’s actually quite common. Gynecomastia affects an estimated 40 to 60 percent of men. It may affect only one breast or both. Though certain drugs and medical problems have been linked with male breast overdevelopment, there is no known cause in the vast majority of cases.
For men who feel self-conscious about their appearance, breast-reduction surgery can help. The procedure removes fat and or glandular tissue from the breasts, and in extreme cases removes excess skin, resulting in a chest that is flatter, firmer, and better contoured.
If you’re considering surgery to correct gynecomastia, this information will give you a basic understanding of the procedure–when it can help, how it’s performed, and what results you can expect. It can’t answer all of your questions, since a lot depends on your individual circumstances. Please be sure to ask your doctor if there is anything about the procedure you don’t understand.
The best candidates for gynecomastia correction
Surgery to correct gynecomastia can be performed on healthy, emotionally stable men of any age. The best candidates for surgery have firm, elastic skin that will reshape to the body’s new contours.
Surgery may be discouraged for obese men, or for overweight men who have not first attempted to correct the problem with exercise or weight loss. Also, individuals who drink alcohol beverages in excess or smoke marijuana are usually not considered good candidates for surgery. These drugs, along with anabolic steroids, may cause gynecomastia. Therefore, patients are first directed to stop the use of these drugs to see if the breast fullness will diminish before surgery is considered an option.
All surgery carries some uncertainty and risk
When male breast-reduction surgery is performed by a qualified plastic surgeon, complications are infrequent and usually minor. Nevertheless, as with any surgery, there are risks. These include infection, skin injury, excessive bleeding, adverse reaction to anesthesia, and excessive fluid loss or accumulation. The procedure may also result in noticeable scars, permanent pigment changes in the breast area, or slightly mismatched breasts or nipples. If asymmetry is significant, a second procedure may be performed to remove additional tissue.
The temporary effects of breast reduction include loss of breast sensation or numbness, which may last up to a year.
The initial consultation with your surgeon is very important. Your surgeon will need a complete medical history, so check your own records ahead of time and be ready to provide this information. First, your surgeon will examine your breasts and check for causes of the gynecomastia, such as impaired liver function, use of estrogen-containing medications, or anabolic steroids. If a medical problem is the suspected cause, you’ll be referred to an appropriate specialist.
Your plastic surgeon may, in extreme cases, also recommend a mammogram, or breast x-ray. This will not only rule out the very small possibility of breast cancer, but will reveal the breast’s composition. Once your surgeon knows how much fat and glandular tissue is contained within the breasts, he or she can choose a surgical approach to best suit your needs.
Don’t hesitate to ask your surgeon any questions you may have during the initial consultation- including your concerns about the recommended treatment or the costs involved. Treatment of gynecomastia may be covered by medical insurance–but policies vary greatly. Check your policy or call your carrier to be sure. If you are covered, make certain you get written pre-authorization for the treatment recommended by your surgeon.
Preparing for your surgery
Your surgeon will give you specific instructions on how to prepare for surgery, including guidelines on eating, drinking, and taking certain vitamins and medications.
Smokers should plan to stop smoking for a minimum of one or two weeks before surgery and during recovery. Smoking decreases circulation and interferes with proper healing. Therefore, it is essential to follow all your surgeon’s instructions.
Where your surgery will be performed
Surgery for gynecomastia is most often performed as an outpatient procedure, but in extreme cases, or those where other medical conditions present cause for concern, an overnight hospital stay may be recommended. The surgery itself usually takes about an hour and a half to complete. However, more extensive procedures may take longer.
Type of anesthesia
Correction of enlarged male breasts may be performed under general, or in some cases, under local anesthesia plus sedation. You’ll be awake, but very relaxed and insensitive to pain. More extensive correction may be performed under general anesthesia, which allows the patient to sleep through the entire operation. Your surgeon will discuss which option is recommended for you, and why this is the option of choice.
The surgery
If excess glandular tissue is the primary cause of the breast enlargement, it will be excised, or cut out, with a scalpel. The excision may be performed alone or in conjunction with liposuction. In a typical procedure, an incision is made in an inconspicuous location–either on the edge of the areola or in the under arm area. Working through the incision, the surgeon cuts away the excess glandular tissue, fat and skin from around the areola and from the sides and bottom of the breast. Major reductions that involve the removal of a significant amount of tissue and skin may require larger incisions that result in more conspicuous scars. If liposuction is used to remove excess fat, the cannula is usually inserted through the existing incisions. Talk to your plastic surgeon in Los Angeles.
Categories: Breast Cancer Recovery Tags: breast, gynecomastia, Male, reduction, surgery
Male Breast Reduction Surgery – Gynecomastia
Gynecomastia is a medical term that comes from the Greek words for “women-like breasts.” Though this oddly named condition is rarely talked about, it’s actually quite common. Gynecomastia affects an estimated 40 to 60 percent of men. It may affect only one breast or both. Though certain drugs and medical problems have been linked with male breast overdevelopment, there is no known cause in the vast majority of cases.
For men who feel self-conscious about their appearance, breast-reduction surgery can help. The procedure removes fat and or glandular tissue from the breasts, and in extreme cases removes excess skin, resulting in a chest that is flatter, firmer, and better contoured.
If you’re considering surgery to correct gynecomastia, this information will give you a basic understanding of the procedure–when it can help, how it’s performed, and what results you can expect. It can’t answer all of your questions, since a lot depends on your individual circumstances. Please be sure to ask your doctor if there is anything about the procedure you don’t understand.
The best candidates for gynecomastia correction
Surgery to correct gynecomastia can be performed on healthy, emotionally stable men of any age. The best candidates for surgery have firm, elastic skin that will reshape to the body’s new contours.
Surgery may be discouraged for obese men, or for overweight men who have not first attempted to correct the problem with exercise or weight loss. Also, individuals who drink alcohol beverages in excess or smoke marijuana are usually not considered good candidates for surgery. These drugs, along with anabolic steroids, may cause gynecomastia. Therefore, patients are first directed to stop the use of these drugs to see if the breast fullness will diminish before surgery is considered an option.
All surgery carries some uncertainty and risk
When male breast-reduction surgery is performed by a qualified plastic surgeon, complications are infrequent and usually minor. Nevertheless, as with any surgery, there are risks. These include infection, skin injury, excessive bleeding, adverse reaction to anesthesia, and excessive fluid loss or accumulation. The procedure may also result in noticeable scars, permanent pigment changes in the breast area, or slightly mismatched breasts or nipples. If asymmetry is significant, a second procedure may be performed to remove additional tissue.
The temporary effects of breast reduction include loss of breast sensation or numbness, which may last up to a year.
The initial consultation with your surgeon is very important. Your surgeon will need a complete medical history, so check your own records ahead of time and be ready to provide this information. First, your surgeon will examine your breasts and check for causes of the gynecomastia, such as impaired liver function, use of estrogen-containing medications, or anabolic steroids. If a medical problem is the suspected cause, you’ll be referred to an appropriate specialist.
Your plastic surgeon may, in extreme cases, also recommend a mammogram, or breast x-ray. This will not only rule out the very small possibility of breast cancer, but will reveal the breast’s composition. Once your surgeon knows how much fat and glandular tissue is contained within the breasts, he or she can choose a surgical approach to best suit your needs.
Don’t hesitate to ask your surgeon any questions you may have during the initial consultation- including your concerns about the recommended treatment or the costs involved. Treatment of gynecomastia may be covered by medical insurance–but policies vary greatly. Check your policy or call your carrier to be sure. If you are covered, make certain you get written pre-authorization for the treatment recommended by your surgeon.
Preparing for your surgery
Your surgeon will give you specific instructions on how to prepare for surgery, including guidelines on eating, drinking, and taking certain vitamins and medications.
Smokers should plan to stop smoking for a minimum of one or two weeks before surgery and during recovery. Smoking decreases circulation and interferes with proper healing. Therefore, it is essential to follow all your surgeon’s instructions.
Where your surgery will be performed
Surgery for gynecomastia is most often performed as an outpatient procedure, but in extreme cases, or those where other medical conditions present cause for concern, an overnight hospital stay may be recommended. The surgery itself usually takes about an hour and a half to complete. However, more extensive procedures may take longer.
Type of anesthesia
Correction of enlarged male breasts may be performed under general, or in some cases, under local anesthesia plus sedation. You’ll be awake, but very relaxed and insensitive to pain. More extensive correction may be performed under general anesthesia, which allows the patient to sleep through the entire operation. Your surgeon will discuss which option is recommended for you, and why this is the option of choice.
The surgery
If excess glandular tissue is the primary cause of the breast enlargement, it will be excised, or cut out, with a scalpel. The excision may be performed alone or in conjunction with liposuction. In a typical procedure, an incision is made in an inconspicuous location–either on the edge of the areola or in the under arm area. Working through the incision, the surgeon cuts away the excess glandular tissue, fat and skin from around the areola and from the sides and bottom of the breast. Major reductions that involve the removal of a significant amount of tissue and skin may require larger incisions that result in more conspicuous scars. If liposuction is used to remove excess fat, the cannula is usually inserted through the existing incisions. Talk to your plastic surgeon in Los Angeles.
Categories: Breast Cancer Recovery Tags: breast, gynecomastia, Male, reduction, surgery
